Antitumor Properties of Irinotecan-Containing Nanoparticles Prepared Using Poly(DL-lactic acid) and Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol).
نویسندگان
چکیده
منابع مشابه
Antitumor properties of irinotecan-containing nanoparticles prepared using poly(DL-lactic acid) and poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol).
Irinotecan-containing nanoparticles (NP) were prepared by coprecipitation with addition of water to acetone solution of poly(DL-lactic acid), poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) and irinotecan, and subsequent evaporation of organic solvent. NP were purified by gel filtration and used for experiments after condensation by evaporation. The obtained NP sh...
متن کاملComplete Genome Sequence of Polypropylene Glycol- and Polyethylene Glycol-Degrading Sphingopyxis macrogoltabida Strain EY-1
Strain EY-1 was isolated from a microbial consortium growing on a random polymer of ethylene oxide and propylene oxide. Strain EY-1 grew on polyethylene glycol and polypropylene glycol and identified as Sphingopyxis macrogoltabida. Here, we report the complete genome sequence of Sphingopyxis macrogoltabida EY-1. The genome of strain EY-1 is comprised of a 4.76-Mb circular chromosome, and five p...
متن کاملFabrication of Clotrimazole microparticles using polyethylene glycol 6000 and beeswax
Backgrounds: Microparticles are one of drug delivery systems designed for sustained and controlled release of drugs for a long period of time. Clotrimazole is a broad-spectrum antifungal agent, which is generally used for treatment of Candida albicans and others fungal infections. Objectives: The present study aims to fabricate Clotrimazole microparticles using beeswax (lipophilic coating) an...
متن کاملImmunogenicity of Polyethylene Glycol (PEG)
Covalent attachment of polyethylene glycol (PEG) to active proteins (PEGylation technology) successfully generated several FDA-approved compounds, including four blockbusters, which are considered non immunogenic. However, PEG antibodies and intolerance to the infusion were reported in some patients with gout treated with pegloticase, a PEG-uricase recently approved by the FDA (Food and Drug Ad...
متن کاملEthylene glycol and polyethylene glycol catabolism by a sewage bacterium.
Bioconsequences Section, Unilever Research Port Sunlight Laboratory, Port Sunlight, Wirral, Merseyside L62 4XN, U.K. Polyethylene glycols are an important group of polymers used in the manufacture of explosives, cosmetics and pharmaceuticals. In addition, the polyoxyethylene group is the hydrophilic head group of non-ionic surfactants such as the alcohol ethoxylates used in detergent formulatio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2003
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.26.116